320 Changes in anthropometrical parameters in infants with CF diagnosed through newborn screening (NBS)

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Bronchoscopy in cystic fibrosis infants diagnosed by newborn screening.

BACKGROUND There is evidence of early functional and structural changes in babies with cystic fibrosis (CF) diagnosed on newborn screening (NBS). The aim of the present study was to determine the yield of bronchoalveolar lavage (BAL) microbiology and cytology, and 24 hr pH monitoring in a group of CF infants diagnosed on NBS. METHODS Infants referred to a tertiary pediatric respiratory center...

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Lung function is abnormal in 3-month-old infants with cystic fibrosis diagnosed by newborn screening.

BACKGROUND Long-term benefits of newborn screening (NBS) for cystic fibrosis (CF) have been established with respect to nutritional status, but effects on pulmonary health remain unclear. HYPOTHESIS With early diagnosis and commencement of standardised treatment, lung function at ∼3 months of age is normal in NBS infants with CF. METHODS Lung clearance index (LCI) and functional residual ca...

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Characterization of mortality in children with sickle cell disease diagnosed through the Newborn Screening Program.

OBJECTIVE To characterize the deaths of 193 children with sickle cell disease screened by a neonatal program from 1998 to 2012 and contrast the initial years with the final years. METHODS Deaths were identified by active surveillance of children absent to scheduled appointments in Blood Bank Clinical Centers (Hemominas). Clinical and epidemiological data came from death certificates, neonatal...

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Characterization of mortality in children with sickle cell disease diagnosed through the Newborn Screening

Objective: To characterize the deaths of 193 children with sickle cell disease screened by a neonatal program from 1998 to 2012 and contrast the initial years with the final years. Methods: Deaths were identified by active surveillance of children absent to scheduled appointments in Blood Bank Clinical Centers (Hemominas). Clinical and epidemiological data came from death certificates, neonatal...

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ژورنال

عنوان ژورنال: Journal of Cystic Fibrosis

سال: 2017

ISSN: 1569-1993

DOI: 10.1016/s1569-1993(17)30658-6